All Phenotypes Mmp21<b2b873Clo> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Mmp21^b2b873Clo
Bench to Bassinet Program (B2B/CVDC), mutation 873 Cecilia Lo
MGI:5311376

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mmp21^b2b873Clo/Mmp21^b2b873Clo	C57BL/6J-Mmp21^b2b873Clo	MGI:5313515

Allelic Composition	Mmp21^b2b873Clo/Mmp21^b2b873Clo
Genetic Background	C57BL/6J-Mmp21^b2b873Clo

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mmp21^b2b873Clo mutation (1 available); any Mmp21 mutation (28 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Dextrocardia with anterior aorta, right pulmonary isomerism with bilateral 3 lung lobes, and mirror symmetric liver situs.

cardiovascular system

tricuspid valve atresia ( J:175213 )

ventricular septal defect ( J:175213 )

growth/size/body

heterotaxia ( J:175213 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
visceral heterotaxy		DOID:0050545	OMIM:306955 OMIM:605376 OMIM:606325 OMIM:613751 OMIM:614779 OMIM:PS306955	J:175213

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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