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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rhbdf1/Hbatm2Ajhs
targeted mutation 2, Andrew JH Smith
MGI:5309140
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rhbdf1/Hbatm2Ajhs/Rhbdf1/Hbatm2Ajhs involves: 129P2/OlaHsd * C57BL/6 MGI:5309163
ht2
 		Rhbdf1/Hbatm2Ajhs/Hba+ involves: 129P2/OlaHsd * C57BL/6 MGI:5309165


Genotype
MGI:5309163
hm1
Allelic
Composition		 Rhbdf1/Hbatm2Ajhs/Rhbdf1/Hbatm2Ajhs
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rhbdf1/Hbatm2Ajhs mutation (0 available); any Hba mutation (11 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality during organogenesis, complete penetrance ( J:117887 )
• by E11.5, mice die presumably from severe anemia

hematopoietic system
anemia ( J:117887 )
• by E11.5, mice die presumably from severe anemia

embryo

integument
pallor ( J:117887 )
• by E11.5

growth/size/body
decreased embryo size ( J:117887 )
• by E11.5




Genotype
MGI:5309165
ht2
Allelic
Composition		 Rhbdf1/Hbatm2Ajhs/Hba+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rhbdf1/Hbatm2Ajhs mutation (0 available); any Hba mutation (11 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory