About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tc(HSA14)SC20Ktom
transchromosomal, human 14, line SC20, Kazuma Tomizuka
MGI:5305481
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Ightm1Ktom/Ightm1Ktom
Igktm1Ktom/Igktm1Ktom
Tc(HSA14)SC20Ktom/0
Tc(HSA2)W23Ktom/0 		involves: C57BL/6NCrlj * CBA/JNCrlj * ICR MGI:5305486


Genotype
MGI:5305486
cx1
Allelic
Composition		 Ightm1Ktom/Ightm1Ktom
Igktm1Ktom/Igktm1Ktom
Tc(HSA14)SC20Ktom/0
Tc(HSA2)W23Ktom/0
Genetic
Background		 involves: C57BL/6NCrlj * CBA/JNCrlj * ICR
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ightm1Ktom mutation (0 available); any Igh mutation (43 available)
Igktm1Ktom mutation (0 available); any Igk mutation (25 available)
Tc(HSA14)SC20Ktom mutation (0 available); any Tc(HSA14)SC20Ktom mutation (0 available)
Tc(HSA2)W23Ktom mutation (0 available); any Tc(HSA2)W23Ktom mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal B cell physiology ( J:59894 )
• mice express human immunoglobulins
• however, B cell development is normal

hematopoietic system
abnormal B cell physiology ( J:59894 )
• mice express human immunoglobulins
• however, B cell development is normal




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory