Phenotypes associated with this allele
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ightm1Ktom mutation
(0 available);
any
Igh mutation
(43 available)
Igktm1Ktom mutation
(0 available);
any
Igk mutation
(25 available)
Tc(HSA14)SC20Ktom mutation
(0 available);
any
Tc(HSA14)SC20Ktom mutation
(0 available)
Tc(HSA2)W23Ktom mutation
(0 available);
any
Tc(HSA2)W23Ktom mutation
(0 available)
|
|
|
immune system
|
• mice express human immunoglobulins
• however, B cell development is normal
|
hematopoietic system
|
• mice express human immunoglobulins
• however, B cell development is normal
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ightm1Ktom mutation
(0 available);
any
Igh mutation
(43 available)
Tc(HSA2)W23Ktom mutation
(0 available);
any
Tc(HSA2)W23Ktom mutation
(0 available)
|
|
|
immune system
|
• B cells exhibit expression of human IGH locus
• however, mice exhibit restored B cell development
|
hematopoietic system
|
• B cells exhibit expression of human IGH locus
• however, mice exhibit restored B cell development
|