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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Slc34a2tm1Sega
targeted mutation 1, Hiroko Segawa
MGI:5305039
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Slc34a2tm1Sega/Slc34a2tm1Sega involves: 129S6/SvEvTac * C57BL/6JJcl MGI:5305042
ht2
Slc34a2tm1Sega/Slc34a2+ involves: 129S6/SvEvTac * C57BL/6JJcl MGI:5305043


Genotype
MGI:5305042
hm1
Allelic
Composition
Slc34a2tm1Sega/Slc34a2tm1Sega
Genetic
Background
involves: 129S6/SvEvTac * C57BL/6JJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc34a2tm1Sega mutation (0 available); any Slc34a2 mutation (39 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging

embryo




Genotype
MGI:5305043
ht2
Allelic
Composition
Slc34a2tm1Sega/Slc34a2+
Genetic
Background
involves: 129S6/SvEvTac * C57BL/6JJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc34a2tm1Sega mutation (0 available); any Slc34a2 mutation (39 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• in an adenine-induced renal failure model
• at 4, but not 20, weeks of age
• at 4, but not 20, weeks of age
• in an adenine-induced renal failure model
• increased in the plasma at 4 weeks of age
• at 4, but not 20, weeks of age
• at 4 and 20 weeks of age
• in an adenine-induced renal failure model, mice exhibit decreased plasma creatinine, phosphate, and calcium compared with wild-type mice

digestive/alimentary system
• at 4 and 20 weeks of age, sodium-dependent phosphate transport activity is decreased in the distal intestine compared to in wild-type mice
• however, uptake in the proximal intestine is normal

renal/urinary system
• at 4, but not 20, weeks of age
• at 4 and 20 weeks of age





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory