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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dscamtm1.1Pfu
targeted mutation 1.1, Peter G Fuerst
MGI:5305025
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Dscamtm1.1Pfu/Dscamtm1.1Pfu involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:5305030


Genotype
MGI:5305030
hm1
Allelic
Composition		 Dscamtm1.1Pfu/Dscamtm1.1Pfu
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dscamtm1.1Pfu mutation (0 available); any Dscam mutation (107 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal amacrine cell morphology ( J:179393 )
• dopaminergic amacrine cells and neurites are clumped
• lamination defects in bNOS-positive amacrine cells

nervous system
abnormal axon fasciculation ( J:179393 )
• of retinal dopaminergic and bNOS positive amacrine cell neurites
abnormal amacrine cell morphology ( J:179393 )
• dopaminergic amacrine cells and neurites are clumped
• lamination defects in bNOS-positive amacrine cells

cellular
abnormal axon fasciculation ( J:179393 )
• of retinal dopaminergic and bNOS positive amacrine cell neurites




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory