All Phenotypes Lbx1<tm1.1Khan> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Lbx1^tm1.1Khan
targeted mutation 1.1, Kazunori Hanaoka
MGI:5304400

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lbx1^tm1.1Khan/Lbx1^tm1.1Khan	involves: C57BL/6JJcl * C57BL/6NCrlj * CBA/JNCrlj	MGI:5304416
cn2	Lbx1^tm1.1Khan/Lbx1^tm1.1Khan Myf5^tm3(cre)Sor/Myf5⁺	involves: 129S4/SvJaeSor * C57BL/6JJcl * C57BL/6NCrlj * CBA/JNCrlj	MGI:5304420
cn3	Lbx1^tm1.1Khan/Lbx1^tm1.1Khan Tg(CAG-cre/Esr1*)5Amc/0	involves: C57BL/6 * CBA	MGI:5304417

Allelic Composition	Lbx1^tm1.1Khan/Lbx1^tm1.1Khan
Genetic Background	involves: C57BL/6JJcl * C57BL/6NCrlj * CBA/JNCrlj

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lbx1^tm1.1Khan mutation (0 available); any Lbx1 mutation (13 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:178868 )

• mice are viable and fertile and do not exhibit any recognizable external abnormalities

Allelic Composition	Lbx1^tm1.1Khan/Lbx1^tm1.1Khan Myf5^tm3(cre)Sor/Myf5⁺
Genetic Background	involves: 129S4/SvJaeSor * C57BL/6JJcl * C57BL/6NCrlj * CBA/JNCrlj

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lbx1^tm1.1Khan mutation (0 available); any Lbx1 mutation (13 available)
Myf5^tm3(cre)Sor mutation (1 available); any Myf5 mutation (17 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

muscle

abnormal muscle precursor cell migration ( J:178868 )

• impaired

abnormal skeletal muscle morphology ( J:178868 )

• mice exhibit a reduction in limb extensor muscle mass

growth/size/body

decreased body size ( J:178868 )

• somewhat compared with Lbx1^tm1.1Khan homozygotes

cellular

abnormal muscle precursor cell migration ( J:178868 )

• impaired

Allelic Composition	Lbx1^tm1.1Khan/Lbx1^tm1.1Khan Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background	involves: C57BL/6 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lbx1^tm1.1Khan mutation (0 available); any Lbx1 mutation (13 available)
Tg(CAG-cre/Esr1*)5Amc mutation (9 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

muscle

abnormal skeletal muscle morphology ( J:178868 )

• tamoxifen-treated mice lack limb extensor muscles

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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