Phenotypes associated with this allele

• Allele Symbol: Cert1^tm1.1Jsau
• Allele Name: targeted mutation 1.1, Juan Saus
• Allele ID: MGI:5301370
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cert1^tm1.1Jsau/Cert1^tm1.1Jsau	involves: 129S/SvEv * BALB/cJ * C57BL/6	MGI:5301419

Genotype
MGI:5301419

hm1

• Allelic Composition: Cert1^tm1.1Jsau/Cert1^tm1.1Jsau
• Genetic Background: involves: 129S/SvEv * BALB/cJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

reproductive system phenotype ( J:177789 )

N • unlike null mice, fertility is normal

muscle

abnormal muscle development ( J:177789 )

• cultured myoblasts exhibit impaired cell fusion and myotube formation compared with wild-type cells

• differentiating myoblasts exhibit aggregates of fibrillar material (cytoplasmic bodies) unlike wild-type cells

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:177789 )

N • mice exhibit normal performance in exhaustion trials