Phenotypes associated with this allele

• Allele Symbol: Tg(Ckm-Fstl1)#Mvdh
• Allele Name: transgene insertion, Maurice JB van den Hoff
• Allele ID: MGI:5297551
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(Ckm-Fstl1)#Mvdh/0	involves: C57BL/6	MGI:5297553

Genotype
MGI:5297553

tg1

• Allelic Composition: Tg(Ckm-Fstl1)#Mvdh/0
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

increased angiogenesis ( J:177416 )

• following pressure overload, the increase in myocardial capillary density is more than in wild-type mice

increased myocardial fiber size ( J:177416 )

• not as severe as in wild-type mice following pressure overload

abnormal coronary vessel morphology ( J:177416 )

• following pressure overload, the increase in myocardial capillary density is more than in wild-type mice

increased heart weight ( J:177416 )

• not as severe as in wild-type mice following pressure overload

increased heart left ventricle weight ( J:177416 )

• not as severe as in wild-type mice following pressure overload

cardiac fibrosis ( J:177416 )

• not as severe as in wild-type mice following pressure overload

decreased cardiac muscle contractility ( J:177416 )

• not as severe as in wild-type mice following pressure overload

decreased response of heart to induced stress ( J:177416 )

• following pressure overload, mice are protected from cardiac hypertrophy and remodeling compared with wild-type mice

homeostasis/metabolism

decreased response of heart to induced stress ( J:177416 )

• following pressure overload, mice are protected from cardiac hypertrophy and remodeling compared with wild-type mice

muscle

increased myocardial fiber size ( J:177416 )

• not as severe as in wild-type mice following pressure overload

decreased cardiac muscle contractility ( J:177416 )

• not as severe as in wild-type mice following pressure overload

growth/size/body

increased heart weight ( J:177416 )

• not as severe as in wild-type mice following pressure overload