About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cd247m1Btlr
mutation 1, Bruce Beutler
MGI:5297360
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cd247m1Btlr/Cd247m1Btlr C57BL/6J-Cd247m1Btlr MGI:5297490


Genotype
MGI:5297490
hm1
Allelic
Composition		 Cd247m1Btlr/Cd247m1Btlr
Genetic
Background		 C57BL/6J-Cd247m1Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd247m1Btlr mutation (1 available); any Cd247 mutation (11 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal CD4-positive, alpha-beta T cell physiology ( J:158794 )
• following sublethal irradiation and repopulation with wild-type bone marrow cells, CD4+ T cells from homozygous mice are outcompeted by wild type cells

hematopoietic system
abnormal CD4-positive, alpha-beta T cell physiology ( J:158794 )
• following sublethal irradiation and repopulation with wild-type bone marrow cells, CD4+ T cells from homozygous mice are outcompeted by wild type cells




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory