Analysis Tools
behavior/neurological
| N |
• mice exhibit normal cue-conditioning, electric shock sensitivity, and latent inhibition of tone-dependent freezing
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• in an elevated plus maze, mice spend more time in the open arms and less time in closed arms compared with wild-type mice
• however, clozapine treatment ameliorated performance in the elevated plus maze
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• increased exploration in male mice
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• in female mice but not male mice
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• in an open field test, female mice exhibit increased distance traveled in the inner area compared with wild-type mice
• however, male mice exhibit normal activity in an open field test
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• methamphetamine-induced, especially in female mice
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• mice exhibit a slight increase in social interaction time compared with wild-type mice
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nervous system
| N |
• mice exhibit normal brain development
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• mice exhibit short-term potentiation following a protocol that induces long-term depression in wild-type mice
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• the threshold to induce long-term potentiation induction is increased compared to in wild-type mice
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• in female mice but not male mice
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• mice exhibit short-term potentiation following a protocol that induces long-term depression in wild-type mice
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homeostasis/metabolism
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• slight in the cerebellum
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