All Phenotypes Vps45<tm1a(EUCOMM)Hmgu> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Vps45^{tm1a(EUCOMM)Hmgu}
targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
MGI:5296588

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Vps45^{tm1a(EUCOMM)Hmgu}/Vps45^{tm1a(EUCOMM)Hmgu}	involves: C57BL/6N	MGI:7387152

Allelic Composition	Vps45^{tm1a(EUCOMM)Hmgu}/Vps45^{tm1a(EUCOMM)Hmgu}
Genetic Background	involves: C57BL/6N
Cell Lines	HEPD0764_7_D04

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vps45^{tm1a(EUCOMM)Hmgu} mutation (0 available); any Vps45 mutation (28 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality between implantation and placentation, complete penetrance ( J:331313 )

• embryonic lethality around E7.5

embryo

abnormal germ layer development ( J:331313 )

• cell layers of embryos show an overall smaller cell mass and appear as disorganized structures such that germ layers cannot be discriminated, indicating impaired germ layer formation

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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