All Phenotypes Flt4<tm1.2Yhe> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Flt4^tm1.2Yhe
targeted mutation 1.2, Yulong He
MGI:5295072

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Flt4^tm1.2Yhe/Flt4^tm1.2Yhe	involves: 129/Sv * C57BL/6J * FVB/N	MGI:5295150

Allelic Composition	Flt4^tm1.2Yhe/Flt4^tm1.2Yhe
Genetic Background	involves: 129/Sv * C57BL/6J * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Flt4^tm1.2Yhe mutation (0 available); any Flt4 mutation (76 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

abnormal lymphangiogenesis ( J:177405 )

• lymphangiogenic sprouting is disrupted

• however, lymph sacs form

absent lymphatic vessels ( J:177405 )

homeostasis/metabolism

edema ( J:177405 )

• at E15.5

cardiovascular system

cardiovascular system phenotype ( J:177405 )

N	• the blood vascular network forms normally

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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