All Phenotypes Pax3<tm6.2Buck> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Pax3^tm6.2Buck
targeted mutation 6.2, Margaret E Buckingham
MGI:5291823

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pax3^tm6.2Buck/Pax3^tm6.2Buck	involves: 129S2/SvPas * C57BL/6 * SJL	MGI:5291828
ht2	Pax3^{tm6.1(Pax8)Buck}/Pax3^tm6.2Buck	involves: 129S2/SvPas * BALB/c * C57BL/6 * SJL	MGI:5291829

Allelic Composition	Pax3^tm6.2Buck/Pax3^tm6.2Buck
Genetic Background	involves: 129S2/SvPas * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pax3^tm6.2Buck mutation (1 available); any Pax3 mutation (50 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

exencephaly ( J:176192 )

• in 65% of mice

Allelic Composition	Pax3^{tm6.1(Pax8)Buck}/Pax3^tm6.2Buck
Genetic Background	involves: 129S2/SvPas * BALB/c * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pax3^{tm6.1(Pax8)Buck} mutation (0 available); any Pax3 mutation (50 available)
Pax3^tm6.2Buck mutation (1 available); any Pax3 mutation (50 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

embryo

abnormal neural tube morphology ( J:176192 )

• authors state that mice exhibit the same phenotype at E11.5 and other stages as in Pax3^Sp mice

muscle

abnormal muscle development ( J:176192 )

• authors state that mice exhibit the same phenotype at E11.5 and other stages as in Pax3^Sp mice

nervous system

abnormal neural tube morphology ( J:176192 )

• authors state that mice exhibit the same phenotype at E11.5 and other stages as in Pax3^Sp mice

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