Analysis Tools
mortality/aging
|
• all mice die between implantation and E10.5
|
|
Allele Symbol Allele Name Allele ID |
Ppp2r1atm1.2Wltr targeted mutation 1.2, Gernot Walter MGI:5287362 |
||||||||||||||||||||
| Summary |
4 genotypes
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• all mice die between implantation and E10.5
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• benzopyrene-treated mice exhibit increased incidence of lung cancer compared with similarly treated wild-type mice
• however, treatment with a dominant negative Trp53 restores normal induced tumor rates
|
|
• benzopyrene-treated mice exhibit increased incidence of lung cancer compared with similarly treated wild-type mice
• however, treatment with a dominant negative Trp53 restores normal induced tumor rates
|
|
• benzopyrene-treated mice exhibit increased incidence of lung cancer compared with similarly treated wild-type mice
• however, treatment with a dominant negative Trp53 restores normal induced tumor rates
|
|
• benzopyrene-treated mice exhibit increased incidence of lung cancer compared with similarly treated wild-type mice
• however, treatment with a dominant negative Trp53 restores normal induced tumor rates
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• benzopyrene-treated mice exhibit increased incidence of lung cancer (adenomas and adenocarcinomas) compared with similarly treated wild-type mice
• however, treatment with a dominant negative Trp53 restores normal induced tumor rates
|
|
• benzopyrene-treated mice exhibit increased incidence of lung cancer (adenomas and adenocarcinomas) compared with similarly treated wild-type mice
• however, treatment with a dominant negative Trp53 restores normal induced tumor rates
|
|
• in benzopyrene-treated mice
|
|
• in benzopyrene-treated mice
|
|
• benzopyrene-treated mice exhibit increased incidence of lung cancer (adenomas and adenocarcinomas) compared with similarly treated wild-type mice
• however, treatment with a dominant negative Trp53 restores normal induced tumor rates
|
|
• benzopyrene-treated mice exhibit increased incidence of lung cancer (adenomas and adenocarcinomas) compared with similarly treated wild-type mice
• however, treatment with a dominant negative Trp53 restores normal induced tumor rates
|
|
• in benzopyrene-treated mice
|
|
• in benzopyrene-treated mice
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• mice die 6 days after tamoxifen treatment
|
|
• in tamoxifen-treated mice
|
|
• in tamoxifen-treated mice beyond the initial drop associated with tamoxifen treatment alone
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 05/07/2024 MGI 6.23 |
|
|
|
||