All Phenotypes Nrl<tm1.1(Thrb)Df> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Nrl^{tm1.1(Thrb)Df}
targeted mutation 1.1, Douglas Forrest
MGI:5285194

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nrl^{tm1.1(Thrb)Df}/Nrl^{tm1.1(Thrb)Df}	involves: C57BL/6	MGI:5285195

Allelic Composition	Nrl^{tm1.1(Thrb)Df}/Nrl^{tm1.1(Thrb)Df}
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nrl^{tm1.1(Thrb)Df} mutation (0 available); any Nrl mutation (20 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

absent retina rod cells ( J:174592 )

increased retina cone cell number ( J:174592 )

short photoreceptor outer segment ( J:174592 )

abnormal retina outer nuclear layer morphology ( J:174592 )

• rosette distortion

abnormal eye physiology ( J:174592 )

• overexpress S and M opsin but with a normal distribution

abnormal rod electrophysiology ( J:174592 )

• lack scotopic ERG responses

nervous system

absent retina rod cells ( J:174592 )

increased retina cone cell number ( J:174592 )

short photoreceptor outer segment ( J:174592 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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