All Phenotypes Tdg<tm2.1Abc> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tdg^tm2.1Abc
targeted mutation 2.1, Alfonso Bellacosa
MGI:5285106

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tdg^tm2.1Abc/Tdg^tm2.1Abc	B6.129-Tdg^tm2.1Abc	MGI:5285112

Allelic Composition	Tdg^tm2.1Abc/Tdg^tm2.1Abc
Genetic Background	B6.129-Tdg^tm2.1Abc

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tdg^tm2.1Abc mutation (0 available); any Tdg mutation (23 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• at E10.5

embryo

abnormal embryo turning ( J:174772 )

embryonic growth retardation ( J:174772 )

decreased embryo size ( J:174772 )

cardiovascular system

pericardial effusion ( J:174772 )

cellular

abnormal DNA methylation ( J:174772 )

• abrogation of methylation at the Tat enhancer

homeostasis/metabolism

pericardial effusion ( J:174772 )

growth/size/body

embryonic growth retardation ( J:174772 )

decreased embryo size ( J:174772 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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