All Phenotypes Tdg<tm2.1Abc> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tdg^tm2.1Abc
targeted mutation 2.1, Alfonso Bellacosa
MGI:5285106

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tdg^tm2.1Abc/Tdg^tm2.1Abc	B6.129-Tdg^tm2.1Abc	MGI:5285112

Allelic Composition	Tdg^tm2.1Abc/Tdg^tm2.1Abc
Genetic Background	B6.129-Tdg^tm2.1Abc

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tdg^tm2.1Abc mutation (0 available); any Tdg mutation (24 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• at E10.5

embryo

abnormal embryo turning ( J:174772 )

embryonic growth retardation ( J:174772 )

decreased embryo size ( J:174772 )

cardiovascular system

pericardial effusion ( J:174772 )

cellular

abnormal DNA methylation ( J:174772 )

• abrogation of methylation at the Tat enhancer

homeostasis/metabolism

pericardial effusion ( J:174772 )

growth/size/body

embryonic growth retardation ( J:174772 )

decreased embryo size ( J:174772 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/30/2025 MGI 6.24