Phenotypes associated with this allele

• Allele Symbol: Khsrp^tm1.1Cyc
• Allele Name: targeted mutation 1.1, Ching-Yi Chen
• Allele ID: MGI:5285092
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Khsrp^tm1.1Cyc/Khsrp^tm1.1Cyc	B6.Cg-Khsrp^tm1.1Cyc	MGI:5285096

Genotype
MGI:5285096

hm1

• Allelic Composition: Khsrp^tm1.1Cyc/Khsrp^tm1.1Cyc
• Genetic Background: B6.Cg-Khsrp^tm1.1Cyc

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

decreased susceptibility to Herpesvirales infection induced morbidity/mortality ( J:175084 )

• in HSV-1-infected mice

immune system

increased interferon-beta secretion ( J:175084 )

• in HSV-1-infected mice

decreased susceptibility to Herpesvirales infection ( J:175084 )

• HSV-1-infected mice exhibit increased IFNB production in the brain and decreased viral replication compared with wild-type mice

decreased susceptibility to Herpesvirales infection induced morbidity/mortality ( J:175084 )

• in HSV-1-infected mice