Phenotypes associated with this allele

• Allele Symbol: Pdlim5^tm1Chen
• Allele Name: targeted mutation 1, Ju Chen
• Allele ID: MGI:5284897
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Pdlim5^tm1Chen/Pdlim5^tm1Chen Tg(Tnnt2-cre)5Blh/?	involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6 * DBA/2	MGI:5284901

Genotype
MGI:5284901

cn1

• Allelic Composition: Pdlim5^tm1Chen/Pdlim5^tm1Chen; Tg(Tnnt2-cre)5Blh/?
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6 * DBA/2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

dilated heart left ventricle ( J:175042 )

• left ventricular chamber size is significantly enlarged

dilated cardiomyopathy ( J:175042 )

• develop dilated cardiomyopathy starting at 3 months of age

decreased heart left ventricle muscle contractility ( J:175042 )

• left ventricular function significantly impaired as measured by fractional shortening

muscle

dilated cardiomyopathy ( J:175042 )

• develop dilated cardiomyopathy starting at 3 months of age

decreased heart left ventricle muscle contractility ( J:175042 )

• left ventricular function significantly impaired as measured by fractional shortening

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
dilated cardiomyopathy		DOID:12930	OMIM:PS115200	J:175042