Analysis Tools
growth/size/body
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• increase in heart weight relative to body weight in females
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• about 25% lower in females at 3 - 6 weeks of age increasing to about 30% at over 6 weeks of age compared to wild-type females
• about 10% lower in males at 3 - 18 weeks of age compared to wild-type males, however this difference is not statistically significant
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• in females
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• more pronounced in females than in males
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• increase in liver weight relative to body weight in males and females
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• increase in spleen weight relative to body weight in females
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liver/biliary system
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• increase in liver weight relative to body weight in males and females
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cardiovascular system
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• increase in heart weight relative to body weight in females
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immune system
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• increase in spleen weight relative to body weight in females
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nervous system
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• increase in brain weight relative to body weight in females
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reproductive system
| N |
• despite endogenous gene expression in the placenta, mice are fertile and produce viable offspring although fecundity may be suboptimal
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hematopoietic system
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• increase in spleen weight relative to body weight in females
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