Analysis Tools
reproductive system
| N |
• mice exhibit normal fertility
• male mice exhibit normal sperm parameters
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Allele Symbol Allele Name Allele ID |
Tg(H2-K1-Ifnb1)10Seif transgene insertion 10, Isabelle Seif MGI:5141611 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• mice exhibit normal fertility
• male mice exhibit normal sperm parameters
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• female mice exhibit normal fertility
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• at 6 weeks in the epididymis
• dramatic at 9 weeks
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• at P60
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• disorganized
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• 30% fewer cells at P45
• 70% fewer cells at P60
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• at P60
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• at 9 weeks, male mice are infertile
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• in male mice
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• at P45, fewer proliferating spermatogonia and primary spermatocytes per seminiferous tubules compared with wild-type mice
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• at 9 weeks
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• at 6 weeks
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• at 9 weeks, male mice are infertile
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• at P60
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• disorganized
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• 30% fewer cells at P45
• 70% fewer cells at P60
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• at P60
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• at 6 weeks in the epididymis
• dramatic at 9 weeks
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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