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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Zap70m2Btlr
mutation 2, Bruce Beutler
MGI:5141315
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Zap70m2Btlr/Zap70m2Btlr involves: C57BL/6J MGI:5141397


Genotype
MGI:5141397
hm1
Allelic
Composition		 Zap70m2Btlr/Zap70m2Btlr
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zap70m2Btlr mutation (1 available); any Zap70 mutation (53 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased T cell number ( J:174837 )
• mice exhibit reduced frequencies of CD44hi T cells compared with wild-type mice

hematopoietic system
decreased T cell number ( J:174837 )
• mice exhibit reduced frequencies of CD44hi T cells compared with wild-type mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory