All Phenotypes Neto2<tm1Mci> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Neto2^tm1Mci
targeted mutation 1, Roderick R McInnes
MGI:5141222

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Neto2^tm1Mci/Neto2^tm1Mci	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	MGI:5141223
cx2	Neto1^tm1Mci/Neto1^tm1Mci Neto2^tm1Mci/Neto2^tm1Mci	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	MGI:5141224

Allelic Composition	Neto2^tm1Mci/Neto2^tm1Mci
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Neto2^tm1Mci mutation (1 available); any Neto2 mutation (40 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

nervous system phenotype ( J:174557 )

N	• normal brain morphology and kainate receptor mediated excitatory postsynaptic currents

Allelic Composition	Neto1^tm1Mci/Neto1^tm1Mci Neto2^tm1Mci/Neto2^tm1Mci
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Neto1^tm1Mci mutation (1 available); any Neto1 mutation (42 available)
Neto2^tm1Mci mutation (1 available); any Neto2 mutation (40 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal excitatory postsynaptic currents ( J:174557 )

• deficit in kainate receptor (KAR) mediated EPSCs in mossy fiber-CA3 pyramidal cell synapses is similar to that in mice homozygous for Neto1^tm1Mci alone

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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