All Phenotypes Pdgfrb<tm13(Pdgfrb)Sor> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Pdgfrb^{tm13(Pdgfrb)Sor}
targeted mutation 13, Philippe Soriano
MGI:5140888

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Pdgfrb^{tm13(Pdgfrb)Sor}/Pdgfrb⁺ Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺	involves: 129S4/SvJae * C57BL/6 * CBA	MGI:5140925
cn2	Pdgfrb^{tm13(Pdgfrb)Sor}/Pdgfrb⁺ Meox2^tm1(cre)Sor/Meox2⁺	involves: 129S4/SvJaeSor * C57BL/6	MGI:5140924

Allelic Composition	Pdgfrb^{tm13(Pdgfrb)Sor}/Pdgfrb⁺ Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺
Genetic Background	involves: 129S4/SvJae * C57BL/6 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Edil3^{Tg(Sox2-cre)1Amc} mutation (5 available); any Edil3 mutation (42 available)
Pdgfrb^{tm13(Pdgfrb)Sor} mutation (1 available); any Pdgfrb mutation (84 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:173602 )

• usually by P14

growth/size/body

postnatal growth retardation ( J:173602 )

• during the second week

cardiovascular system

increased aorta wall thickness ( J:173602 )

• during the second week, mice exhibit thickening of the ascending aorta media compared with wild-type mice

Allelic Composition	Pdgfrb^{tm13(Pdgfrb)Sor}/Pdgfrb⁺ Meox2^tm1(cre)Sor/Meox2⁺
Genetic Background	involves: 129S4/SvJaeSor * C57BL/6