All Phenotypes Ccdc88a<tm3.1Mat> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ccdc88a^tm3.1Mat
targeted mutation 3.1, Masahide Takahashi
MGI:5140605

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ccdc88a^tm3.1Mat/Ccdc88a^tm3.1Mat	involves: 129S6/SvEvTac * C57BL/6	MGI:5140721

Allelic Composition	Ccdc88a^tm3.1Mat/Ccdc88a^tm3.1Mat
Genetic Background	involves: 129S6/SvEvTac * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccdc88a^tm3.1Mat mutation (0 available); any Ccdc88a mutation (76 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

premature death ( J:173379 )

• at P52, survival rate is 40%

nervous system

abnormal neuronal precursor cell migration ( J:173379 )

• neuroblasts fail to migrate properly and accumulate in the rostral migratory stream unlike in wild-type mice

abnormal olfactory bulb development ( J:173379 )

abnormal rostral migratory stream morphology ( J:173379 )

• neuroblasts fail to migrate properly and accumulate in the rostral migratory stream unlike in wild-type mice

growth/size/body

weight loss ( J:173379 )

• after P7 and P8

cellular

abnormal neuronal precursor cell migration ( J:173379 )

• neuroblasts fail to migrate properly and accumulate in the rostral migratory stream unlike in wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23