All Phenotypes Ccdc88a<tm3.1Mat> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ccdc88a^tm3.1Mat
targeted mutation 3.1, Masahide Takahashi
MGI:5140605

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ccdc88a^tm3.1Mat/Ccdc88a^tm3.1Mat	involves: 129S6/SvEvTac * C57BL/6	MGI:5140721

Allelic Composition	Ccdc88a^tm3.1Mat/Ccdc88a^tm3.1Mat
Genetic Background	involves: 129S6/SvEvTac * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccdc88a^tm3.1Mat mutation (0 available); any Ccdc88a mutation (74 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

premature death ( J:173379 )

• at P52, survival rate is 40%

nervous system

abnormal neuronal precursor cell migration ( J:173379 )

• neuroblasts fail to migrate properly and accumulate in the rostral migratory stream unlike in wild-type mice

abnormal olfactory bulb development ( J:173379 )

abnormal rostral migratory stream morphology ( J:173379 )

• neuroblasts fail to migrate properly and accumulate in the rostral migratory stream unlike in wild-type mice

growth/size/body

weight loss ( J:173379 )

• after P7 and P8

cellular

abnormal neuronal precursor cell migration ( J:173379 )

• neuroblasts fail to migrate properly and accumulate in the rostral migratory stream unlike in wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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