Phenotypes associated with this allele

• Allele Symbol: Pou2f3^tm1Abek
• Allele Name: targeted mutation 1, Keiko Abe
• Allele ID: MGI:5140071
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pou2f3^tm1Abek/Pou2f3^tm1Abek	involves: 129 * C57BL/6J	MGI:5140072

Genotype
MGI:5140072

hm1

• Allelic Composition: Pou2f3^tm1Abek/Pou2f3^tm1Abek
• Genetic Background: involves: 129 * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

taste/olfaction

abnormal gustatory papilla taste bud morphology ( J:173905 )

• expression analysis indicates expansion of sour taste receptor cells at the expense of sweet, umami and bitter taste receptor cells

abnormal bitter taste sensitivity ( J:173905 )

• show no avoidance of bitter taste

• electrophysiological recordings of peripheral nerves containing gustatory fibers display a significant decrease in their responses to bitter taste

abnormal sweet taste sensitivity ( J:173905 )

• show no preference for sweet taste

• electrophysiological recordings of peripheral nerves containing gustatory fibers display a significant decrease in their responses to sweet taste

abnormal umami taste sensitivity ( J:173905 )

• show no preference for umami taste

• electrophysiological recordings of peripheral nerves containing gustatory fibers display a significant decrease in their responses to umami taste

behavior/neurological

abnormal liquid preference ( J:173905 )

• show no preference for sweet or umami tastes and no avoidance of bitter taste

growth/size/body

abnormal gustatory papilla taste bud morphology ( J:173905 )

• expression analysis indicates expansion of sour taste receptor cells at the expense of sweet, umami and bitter taste receptor cells

digestive/alimentary system

abnormal gustatory papilla taste bud morphology ( J:173905 )

• expression analysis indicates expansion of sour taste receptor cells at the expense of sweet, umami and bitter taste receptor cells

craniofacial

abnormal gustatory papilla taste bud morphology ( J:173905 )

• expression analysis indicates expansion of sour taste receptor cells at the expense of sweet, umami and bitter taste receptor cells