All Phenotypes Twsg1<tm1Aptr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Twsg1^tm1Aptr
targeted mutation 1, Anna Petryk
MGI:5056109

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Tg(Sox10-cre)1Wdr/0 Twsg1^tm1Aptr/Twsg1^tm1Aptr	involves: C57BL/6 * CBA	MGI:5056120

Allelic Composition	Tg(Sox10-cre)1Wdr/0 Twsg1^tm1Aptr/Twsg1^tm1Aptr
Genetic Background	involves: C57BL/6 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Sox10-cre)1Wdr mutation (1 available)
Twsg1^tm1Aptr mutation (0 available); any Twsg1 mutation (20 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

craniofacial

abnormal frontonasal prominence morphology ( J:173627 )

• mice exhibit midline fusion of the frontonasal prominences compared with wild-type mice

fused first pharyngeal arch ( J:173627 )

small first pharyngeal arch ( J:173627 )

embryo

fused first pharyngeal arch ( J:173627 )

small first pharyngeal arch ( J:173627 )

nervous system

abnormal telencephalon development ( J:173627 )

• mice exhibit non-septation of the telencephalic vesicles compared with wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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