Phenotypes associated with this allele

• Allele Symbol: Lgals9^tm1.1Cfg
• Allele Name: targeted mutation 1.1, Consortium for Functional Glycomics
• Allele ID: MGI:5052339
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lgals9^tm1.1Cfg/Lgals9^tm1.1Cfg	involves: C57BL/6	MGI:5615624

Genotype
MGI:5615624

hm1

• Allelic Composition: Lgals9^tm1.1Cfg/Lgals9^tm1.1Cfg
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

increased B cell proliferation ( J:217719 )

abnormal Peyer's patch morphology ( J:217719 )

• increased cell numbers

thymus hyperplasia ( J:217719 )

spleen hyperplasia ( J:217719 )

increased neutrophil cell number ( J:217719 )

• in the blood

increased lymphocyte cell number ( J:217719 )

• in the blood

increased spleen germinal center size ( J:217719 )

• prominent as a result of activation and antibody production

abnormal lymph node germinal center morphology ( J:217719 )

• prominent as a result of activation and antibody production

lymph node hyperplasia ( J:217719 )

enhanced humoral immune response ( J:217719 )

• elevated antibody production

endocrine/exocrine glands

thymus hyperplasia ( J:217719 )

growth/size/body

growth/size/body region phenotype ( J:217719 )

N • mice do not exhibit obesity unlike in other studies

spleen hyperplasia ( J:217719 )

hematopoietic system

increased B cell proliferation ( J:217719 )

thymus hyperplasia ( J:217719 )

spleen hyperplasia ( J:217719 )

increased neutrophil cell number ( J:217719 )

• in the blood

increased lymphocyte cell number ( J:217719 )

• in the blood

increased spleen germinal center size ( J:217719 )

• prominent as a result of activation and antibody production

cellular

increased B cell proliferation ( J:217719 )

digestive/alimentary system

abnormal Peyer's patch morphology ( J:217719 )

• increased cell numbers