All Phenotypes Mgat5b<tm1.1Cfg> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Mgat5b^tm1.1Cfg
targeted mutation 1.1, Consortium for Functional Glycomics
MGI:5052168

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mgat5b^tm1.1Cfg/Mgat5b^tm1.1Cfg	involves: 129S6/SvEvTac	MGI:5615632

Allelic Composition	Mgat5b^tm1.1Cfg/Mgat5b^tm1.1Cfg
Genetic Background	involves: 129S6/SvEvTac

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mgat5b^tm1.1Cfg mutation (1 available); any Mgat5b mutation (66 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

seminiferous tubule degeneration ( J:217719 )

immune system

decreased pre-B cell number ( J:217719 )

• in bone marrow

increased IgG2b level ( J:217719 )

enhanced humoral immune response ( J:217719 )

• in T-dependent antibody production

renal/urinary system

• vacuolations in epithelial cells

skeleton

abnormal bone marrow morphology ( J:217719 )

• higher frequency of IgM+IgD+ and pre-B cells

homeostasis/metabolism

• slight

endocrine/exocrine glands

seminiferous tubule degeneration ( J:217719 )

hematopoietic system

decreased pre-B cell number ( J:217719 )

• in bone marrow

increased IgG2b level ( J:217719 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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