All Phenotypes Tgfb1i1<tm1a(KOMP)Wtsi> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tgfb1i1^{tm1a(KOMP)Wtsi}
targeted mutation 1a, Wellcome Trust Sanger Institute
MGI:5050851

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tgfb1i1^{tm1a(KOMP)Wtsi}/Tgfb1i1^{tm1a(KOMP)Wtsi}	involves: C57BL/6N	MGI:5791899

Allelic Composition	Tgfb1i1^{tm1a(KOMP)Wtsi}/Tgfb1i1^{tm1a(KOMP)Wtsi}
Genetic Background	involves: C57BL/6N
Cell Lines	EPD0817_1_D04

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tgfb1i1^{tm1a(KOMP)Wtsi} mutation (2 available); any Tgfb1i1 mutation (23 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:233538 )

• homozygotes are viable, fertile and healthy with no detectable defects in basic blood and platelet parameters, tail bleeding times, and experimental thrombus formation relative to wild-type controls

• in vitro activation of platelet integrins, degranulation and platelet aggregation are normal under all tested conditions

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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