immune system
| N |
• mice exhibit normal B cell development, surface Ig expression, allelic exclusion, Jkappa region usage, Igkappa gene germline levels, and RS recombination
|
|
• mice exhibit skewed Igkappa gene repertoire with decreased distal and enhanced proximal Vkappa gene usage compared with wild-type mice
|
hematopoietic system
|
• mice exhibit skewed Igkappa gene repertoire with decreased distal and enhanced proximal Vkappa gene usage compared with wild-type mice
|


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