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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gt(ROSA)26Sortm39.1(CAG-hop/EYFP)Hze
targeted mutation 39.1, Hongkui Zeng
MGI:5008455
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Gt(ROSA)26Sortm39.1(CAG-hop/EYFP)Hze/Gt(ROSA)26Sor+ involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J * C57BL/6NCr MGI:5008460
cn2
 		Gt(ROSA)26Sortm39.1(CAG-hop/EYFP)Hze/Gt(ROSA)26Sor+
Shox2tm1.1(cre)Oki/Shox2+ 		involves: 129S/SvEv * 129S6/SvEvTac * C57BL/6 MGI:5576702


Genotype
MGI:5008460
ht1
Allelic
Composition		 Gt(ROSA)26Sortm39.1(CAG-hop/EYFP)Hze/Gt(ROSA)26Sor+
Genetic
Background		 involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J * C57BL/6NCr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm39.1(CAG-hop/EYFP)Hze mutation (0 available); any Gt(ROSA)26Sor mutation (1046 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:172634 )
• mice are viable and fertile




Genotype
MGI:5576702
cn2
Allelic
Composition		 Gt(ROSA)26Sortm39.1(CAG-hop/EYFP)Hze/Gt(ROSA)26Sor+
Shox2tm1.1(cre)Oki/Shox2+
Genetic
Background		 involves: 129S/SvEv * 129S6/SvEvTac * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm39.1(CAG-hop/EYFP)Hze mutation (0 available); any Gt(ROSA)26Sor mutation (1046 available)
Shox2tm1.1(cre)Oki mutation (0 available); any Shox2 mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal nervous system physiology ( J:209344 )
• electrical stimulation of spinal cords to induce locomotor activity is decreased by about 25% when Shox2 interneurons are inactivated by light, which is similar to the phenotype observed when the population of Shox2 interneurons is ablated




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory