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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Lrrn3tm1Lex
targeted mutation 1, Lexicon Pharmaceuticals
MGI:5007228
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Lrrn3tm1Lex/Lrrn3tm1Lex involves: 129S5/SvEvBrd * C57BL/6J MGI:5428886


Genotype
MGI:5428886
hm1
Allelic
Composition		 Lrrn3tm1Lex/Lrrn3tm1Lex
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lrrn3tm1Lex mutation (2 available); any Lrrn3 mutation (33 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
adipose tissue
increased percent body fat/body weight ( J:171883 )
• homozygous mutant mice exhibited increased mean percent body fat

homeostasis/metabolism
improved glucose tolerance ( J:171883 )
• male homozygous mutant mice exhibited enhanced glucose tolerance when compared with controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory