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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Lnx1tm1Lex
targeted mutation 1, Lexicon Pharmaceuticals
MGI:5007219
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Lnx1tm1Lex/Lnx1tm1Lex involves: 129S5/SvEvBrd * C57BL/6J MGI:5429588


Genotype
MGI:5429588
hm1
Allelic
Composition		 Lnx1tm1Lex/Lnx1tm1Lex
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lnx1tm1Lex mutation (2 available); any Lnx1 mutation (43 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
increased B-1b cell number ( J:171883 )
• homozygous mutant mice exhibited an increased percentage of B1-like B cells in peritoneal lavage when compared with that of controls

immune system
increased B-1b cell number ( J:171883 )
• homozygous mutant mice exhibited an increased percentage of B1-like B cells in peritoneal lavage when compared with that of controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory