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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Hdgfl2tm1Lex
targeted mutation 1, Lexicon Pharmaceuticals
MGI:5007175
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Hdgfl2tm1Lex/Hdgfl2tm1Lex involves: 129S5/SvEvBrd * C57BL/6J MGI:5429564


Genotype
MGI:5429564
hm1
Allelic
Composition		 Hdgfl2tm1Lex/Hdgfl2tm1Lex
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hdgfl2tm1Lex mutation (2 available); any Hdgfl2 mutation (50 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
increased circulating alkaline phosphatase level ( J:171883 )
• increased mean serum alkaline phosphatase levels

cellular
decreased fibroblast proliferation ( J:171883 )
• decreased mean skin fibroblast proliferation rate




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory