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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Fcrl2tm1Lex
targeted mutation 1, Lexicon Pharmaceuticals
MGI:5007138
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Fcrl2tm1Lex/Fcrl2tm1Lex B6;129S5-Fcrl2tm1Lex/Mmucd MGI:5829262


Genotype
MGI:5829262
hm1
Allelic
Composition		 Fcrl2tm1Lex/Fcrl2tm1Lex
Genetic
Background		 B6;129S5-Fcrl2tm1Lex/Mmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fcrl2tm1Lex mutation (2 available); any Fcrl2 mutation (41 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
adipose tissue

growth/size/body
increased lean body mass ( J:171883 )
increased total tissue mass ( J:171883 )
increased body size ( J:171883 )
increased body weight ( J:171883 )

hematopoietic system
decreased CD8-positive, alpha-beta T cell number ( J:171883 )
• homozygous mutant mice exhibited a decreased mean percentage of CD8 cells in the peripheral blood

immune system
decreased CD8-positive, alpha-beta T cell number ( J:171883 )
• homozygous mutant mice exhibited a decreased mean percentage of CD8 cells in the peripheral blood




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory