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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Car9tm1Lex
targeted mutation 1, Lexicon Pharmaceuticals
MGI:5007043
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Car9tm1Lex/Car9tm1Lex B6;129S5-Car9tm1Lex/Mmucd MGI:5828268


Genotype
MGI:5828268
hm1
Allelic
Composition		 Car9tm1Lex/Car9tm1Lex
Genetic
Background		 B6;129S5-Car9tm1Lex/Mmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Car9tm1Lex mutation (2 available); any Car9 mutation (48 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
increased mature B cell number ( J:171883 )
• homozygous mutant mice show an increased mean percentage of mature B cells in bone marrow compared with controls

immune system
increased mature B cell number ( J:171883 )
• homozygous mutant mice show an increased mean percentage of mature B cells in bone marrow compared with controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory