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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Atp13a5tm1Lex
targeted mutation 1, Lexicon Pharmaceuticals
MGI:5007030
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Atp13a5tm1Lex/Atp13a5tm1Lex B6;129S5-Atp13a5tm1Lex/Mmucd MGI:5827987


Genotype
MGI:5827987
hm1
Allelic
Composition		 Atp13a5tm1Lex/Atp13a5tm1Lex
Genetic
Background		 B6;129S5-Atp13a5tm1Lex/Mmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atp13a5tm1Lex mutation (2 available); any Atp13a5 mutation (77 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased NK cell number ( J:171883 )
• homozygous mutant mice exhibited a decreased mean percentage of natural killer cells compared with controls

immune system
decreased NK cell number ( J:171883 )
• homozygous mutant mice exhibited a decreased mean percentage of natural killer cells compared with controls

nervous system
reduced sensorimotor gating ( J:171883 )
• male homozygous mutant mice show impaired sensorimotor gating/attention during prepulse inhibition testing




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory