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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Alg2tm1Lex
targeted mutation 1, Lexicon Pharmaceuticals
MGI:5007020
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Alg2tm1Lex/Alg2tm1Lex B6;129S5-Alg2tm1Lex/Mmucd MGI:5829190
ht2
 		Alg2tm1Lex/Alg2+ B6;129S5-Alg2tm1Lex/Mmucd MGI:5829191


Genotype
MGI:5829190
hm1
Allelic
Composition		 Alg2tm1Lex/Alg2tm1Lex
Genetic
Background		 B6;129S5-Alg2tm1Lex/Mmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Alg2tm1Lex mutation (2 available); any Alg2 mutation (18 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:5829191
ht2
Allelic
Composition		 Alg2tm1Lex/Alg2+
Genetic
Background		 B6;129S5-Alg2tm1Lex/Mmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Alg2tm1Lex mutation (2 available); any Alg2 mutation (18 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
decreased dermal fibroblast proliferation ( J:171883 )
• female heterozygous mice exhibited a decreased mean skin fibroblast proliferation rate when compared with controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory