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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tmem234tm1Lex
targeted mutation 1, Lexicon Pharmaceuticals
MGI:5006992
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Tmem234tm1Lex/Tmem234tm1Lex B6;129S5-Tmem234tm1Lex/Mmucd MGI:5827825


Genotype
MGI:5827825
hm1
Allelic
Composition		 Tmem234tm1Lex/Tmem234tm1Lex
Genetic
Background		 B6;129S5-Tmem234tm1Lex/Mmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tmem234tm1Lex mutation (1 available); any Tmem234 mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
increased IgG2a level ( J:171883 )
• omozygous mutant mice exhibited an increased median serum IgG2a response to ovalbumin challenge when compared with that of their wild-type littermates

immune system
increased IgG2a level ( J:171883 )
• omozygous mutant mice exhibited an increased median serum IgG2a response to ovalbumin challenge when compared with that of their wild-type littermates




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory