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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Glmptm1Lex
targeted mutation 1, Lexicon Pharmaceuticals
MGI:5006986
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Glmptm1Lex/Glmptm1Lex B6;129S5-Glmptm1Lex/Mmucd MGI:5827785


Genotype
MGI:5827785
hm1
Allelic
Composition		 Glmptm1Lex/Glmptm1Lex
Genetic
Background		 B6;129S5-Glmptm1Lex/Mmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Glmptm1Lex mutation (2 available); any Glmp mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system

homeostasis/metabolism
decreased circulating glucose level ( J:171883 )
• decreased mean serum glucose levels
increased circulating alkaline phosphatase level ( J:171883 )
• increased mean serum alkaline phosphatase levels

immune system
abnormal immune system physiology ( J:171883 )
• immunological abnormalities
liver inflammation ( J:171883 )
• mild-to-moderate necrotizing hepatitis

liver/biliary system
liver inflammation ( J:171883 )
• mild-to-moderate necrotizing hepatitis
small liver ( J:171883 )
• smaller than normal upon gross examination




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory