Phenotypes associated with this allele

• Allele Symbol: Pdcd10^tm1.1Wami
• Allele Name: targeted mutation 1.1, Wang Min
• Allele ID: MGI:5002631
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pdcd10^tm1.1Wami/Pdcd10^tm1.1Wami	involves: 129 * C57BL/6	MGI:5002663

Genotype
MGI:5002663

hm1

• Allelic Composition: Pdcd10^tm1.1Wami/Pdcd10^tm1.1Wami
• Genetic Background: involves: 129 * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:171969 )

• all mice are dead by E9.5

embryonic lethality between somite formation and embryo turning, incomplete penetrance ( J:171969 )

• Mendelian ratios could not be detected after E8.5

cardiovascular system

abnormal vasculogenesis ( J:171969 )

• at E8.5

myocardial trabeculae hypoplasia ( J:171969 )

thin myocardium ( J:171969 )

hematopoietic system

anemia ( J:171969 )

• at E8.0

impaired hematopoiesis ( J:171969 )

• yolk sacs lack blood cell-filled vessels

growth/size/body

decreased embryo size ( J:171969 )

• at E8.0

integument

pallor ( J:171969 )

• at E8.0

embryo

decreased embryo size ( J:171969 )

• at E8.0

muscle

myocardial trabeculae hypoplasia ( J:171969 )

thin myocardium ( J:171969 )