All Phenotypes Pdzd2<Gt(S7-9G1)Sor> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Pdzd2^{Gt(S7-9G1)Sor}
gene trap S7-9G1, Philippe Soriano
MGI:4974441

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pdzd2^{Gt(S7-9G1)Sor}/Pdzd2^{Gt(S7-9G1)Sor}	involves: 129S/SvEv * 129S4/SvJaeSor	MGI:6719521

Allelic Composition	Pdzd2^{Gt(S7-9G1)Sor}/Pdzd2^{Gt(S7-9G1)Sor}
Genetic Background	involves: 129S/SvEv * 129S4/SvJaeSor

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pdzd2^{Gt(S7-9G1)Sor} mutation (0 available); any Pdzd2 mutation (102 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

increased insulin secretion ( J:307008 )

• basal and following low concentration glucose stimulation due to altered potassium-ATP channel

decreased circulating glucose level ( J:307008 )

• in the random-fed state

increased circulating insulin level ( J:307008 )

• slightly in the random-fed state

improved glucose tolerance ( J:307008 )

• in mice older than 1 month of age without a change in insulin tolerance

endocrine/exocrine glands

increased insulin secretion ( J:307008 )

• basal and following low concentration glucose stimulation due to altered potassium-ATP channel

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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