About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Flot2Gt(258D8)Cmhd
gene trap 258D8, Centre for Modeling Human Disease
MGI:4968139
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Flot1tm1.1Arte/Flot1tm1.1Arte
Flot2Gt(258D8)Cmhd/Flot2Gt(258D8)Cmhd
Tg(Thy1-APPSw,Thy1-PSEN1*L166P)21Jckr/? 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6J MGI:5697919


Genotype
MGI:5697919
cx1
Allelic
Composition		 Flot1tm1.1Arte/Flot1tm1.1Arte
Flot2Gt(258D8)Cmhd/Flot2Gt(258D8)Cmhd
Tg(Thy1-APPSw,Thy1-PSEN1*L166P)21Jckr/?
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Flot1tm1.1Arte mutation (0 available); any Flot1 mutation (18 available)
Flot2Gt(258D8)Cmhd mutation (0 available); any Flot2 mutation (37 available)
Tg(Thy1-APPSw,Thy1-PSEN1*L166P)21Jckr mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
amyloid beta deposits ( J:212342 )
• reduced quantity of Abeta fragments

nervous system
amyloid beta deposits ( J:212342 )
• reduced quantity of Abeta fragments




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory