Phenotypes associated with this allele

• Allele Symbol: Cables2^{tm1(KOMP)Vlcg}
• Allele Name: targeted mutation 1, Velocigene
• Allele ID: MGI:4951297
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cables2^tm1(KOMP)Vlcg/Cables2^tm1(KOMP)Vlcg	C57BL/6NTac-Cables2^tm1(KOMP)Vlcg	MGI:6761766

Genotype
MGI:6761766

hm1

• Allelic Composition: Cables2^{tm1(KOMP)Vlcg}/Cables2^{tm1(KOMP)Vlcg}
• Genetic Background: C57BL/6NTac-Cables2^{tm1(KOMP)Vlcg}
• Cell Lines: 16085A-D3

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:309963 )

• no mice are detected at or beyond E12.5

embryo

embryonic growth arrest ( J:309963 )

• growth and patterning arrest in gastrulation

embryonic growth retardation ( J:309963 )

• mice do not progress beyond early- to mid-gastrula cylindrical morphology

decreased embryo size ( J:309963 )

• at E7.5 to E9.5

growth/size/body

embryonic growth retardation ( J:309963 )

• mice do not progress beyond early- to mid-gastrula cylindrical morphology

decreased embryo size ( J:309963 )

• at E7.5 to E9.5

cellular

increased apoptosis ( J:309963 )

• at E7.5