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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Ccr2-EGFP)8Pame
transgene insertion 8, Eric G Pamer
MGI:4950277
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Ccl2tm1Rol/Ccl2tm1Rol
Tg(Ccr2-EGFP)8Pame/0 		involves: 129S4/SvJae * C57BL/6J MGI:4950285


Genotype
MGI:4950285
cx1
Allelic
Composition		 Ccl2tm1Rol/Ccl2tm1Rol
Tg(Ccr2-EGFP)8Pame/0
Genetic
Background		 involves: 129S4/SvJae * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccl2tm1Rol mutation (2 available); any Ccl2 mutation (23 available)
Tg(Ccr2-EGFP)8Pame mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal leukocyte migration ( J:171379 )
• monocytes from LPS-treated mice fail to enter the lumen of the blood vessel unlike in wild-type mice

cellular
abnormal leukocyte migration ( J:171379 )
• monocytes from LPS-treated mice fail to enter the lumen of the blood vessel unlike in wild-type mice

hematopoietic system
abnormal leukocyte migration ( J:171379 )
• monocytes from LPS-treated mice fail to enter the lumen of the blood vessel unlike in wild-type mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory