About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Snx27tm1Lslo
targeted mutation 1, Li Shen Loo
MGI:4949192
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Snx27tm1Lslo/Snx27tm1Lslo involves: 129P2/OlaHsd MGI:4949194


Genotype
MGI:4949194
hm1
Allelic
Composition		 Snx27tm1Lslo/Snx27tm1Lslo
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Snx27tm1Lslo mutation (0 available); any Snx27 mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, complete penetrance ( J:171001 )
• all mice born die within the first 3 weeks after birth
prenatal lethality, incomplete penetrance ( J:171001 )
• fewer than expected mice are born

growth/size/body
postnatal growth retardation ( J:171001 )
• mice fail to thrive after birth
slow postnatal weight gain ( J:171001 )

cellular
abnormal cell physiology ( J:171001 )
• endocytosis of Grin2c (NR2C) in cerebellar neurons is impaired compared to in wild-type cells

cardiovascular system

digestive/alimentary system
abnormal intestine morphology ( J:171001 )
• small sized intestine

hematopoietic system

liver/biliary system

immune system




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory