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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Grntm1Far
targeted mutation 1, Bob Farese
MGI:4949109
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Grntm1Far/Grntm1Far involves: 129S4/SvJae * C57BL/6J * FVB/N MGI:5444202
cn2
Grntm1Far/Grntm1Far
Tg(ITGAM-cre)2781Gkl/0
involves: 129S4/SvJae * C57BL/6 * CBA * FVB/N MGI:5444201


Genotype
MGI:5444202
cn1
Allelic
Composition
Grntm1Far/Grntm1Far
Genetic
Background
involves: 129S4/SvJae * C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Grntm1Far mutation (1 available); any Grn mutation (44 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• following treated with LPS and IFN-gamma, primary cultures from mice infected a lentivirus expressing cre in microglia exhibit increased neuron death compared with controls




Genotype
MGI:5444201
cn2
Allelic
Composition
Grntm1Far/Grntm1Far
Tg(ITGAM-cre)2781Gkl/0
Genetic
Background
involves: 129S4/SvJae * C57BL/6 * CBA * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Grntm1Far mutation (1 available); any Grn mutation (44 available)
Tg(ITGAM-cre)2781Gkl mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• in MPTP-treated mice
• greater in mice treated with MPTP compared with control mice

homeostasis/metabolism

cellular

hematopoietic system
• in MPTP-treated mice

immune system
• in MPTP-treated mice





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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory