All Phenotypes Col1a1<tm1Dab> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Col1a1^tm1Dab
targeted mutation 1, David A Brenner
MGI:4948122

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Col1a1^tm1Dab/Col1a1^tm1Dab	C.129S6-Col1a1^tm1Dab	MGI:4948123

Allelic Composition	Col1a1^tm1Dab/Col1a1^tm1Dab
Genetic Background	C.129S6-Col1a1^tm1Dab

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Col1a1^tm1Dab mutation (0 available); any Col1a1 mutation (166 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

• following bile duct ligation, mice exhibit reduced hepatic fibrosis compared with similarly treated wild-type mice

liver/biliary system

abnormal liver morphology ( J:170561 )

• following bile duct ligation, mice exhibit reduced hepatic fibrosis compared with similarly treated wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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