Phenotypes associated with this allele

• Allele Symbol: Del(2Cd59b-Cd59a)1Jha
• Allele Name: deletion, Chr 2, Jose A Halperin 1
• Allele ID: MGI:4947111
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Del(2Cd59b-Cd59a)1Jha/Del(2Cd59b-Cd59a)1Jha	B6.129-Del(2Cd59b-Cd59a)1Jha	MGI:4947226
cx2	C3^tm1Crr/C3^tm1Crr Del(2Cd59b-Cd59a)1Jha/Del(2Cd59b-Cd59a)1Jha	involves: 129/Sv * 129S4/SvJae * C57BL/6	MGI:4947228

Genotype
MGI:4947226

hm1

• Allelic Composition: Del(2Cd59b-Cd59a)1Jha/Del(2Cd59b-Cd59a)1Jha
• Genetic Background: B6.129-Del(2Cd59b-Cd59a)1Jha

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

oligozoospermia ( J:170754 )

♂

reduced male fertility ( J:170754 )

♂ • progressive loss

hematopoietic system

hemolytic anemia ( J:170754 )

• complement-mediated

decreased hemoglobin content ( J:170754 )

reticulocytosis ( J:170754 )

hemolysis ( J:170754 )

• erythrocytes are more sensitive to complement-mediated lysis compared with wild-type cells

cellular

oligozoospermia ( J:170754 )

♂

Genotype
MGI:4947228

cx2

• Allelic Composition: C3^tm1Crr/C3^tm1Crr; Del(2Cd59b-Cd59a)1Jha/Del(2Cd59b-Cd59a)1Jha
• Genetic Background: involves: 129/Sv * 129S4/SvJae * C57BL/6

hematopoietic system

hematopoietic system phenotype ( J:170754 )

N • mice exhibit normal hematological parameters